THE POLYMER SOCIETY OF KOREA

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세션명 Graduate Student Oral Session (I) (English)
발표장 제5회장
논문코드 O5-10
발표일 2024-04-3
발표시간 15:30-15:45
논문제목 Design of Enhanced Carrier for Ceramide
발표자 최영선
발표자 소속 포항공과대학교 화학공학과
저자 최영선, 임준형, 김혜인, 오광석, 김영기
소속 포항공과대학교 화학공학과
논문초록 Ceramide plays an important role in maintaining skin hydration and preserving the integrity of the skin barrier. So, incorporating sufficient amounts of ceramide in cosmetics is a key objective for the industry. However, the hydrophobic and hydrogen bonding characteristics of ceramide lead to crystallization in aqueous solution, limiting its concentration. In the past, lyotropic liquid crystals were used to contain ceramide, but the carriers are unstable in aqueous solution because of their hydrophilic nature. This paper introduces an enhanced approach in design of ceramide carrier by using thermotropic liquid crystals (TLCs) with hydrophobic characteristics. The results demonstrate that the hydrophobic (TLC) - hydrophilic (aqueous solution) interface significantly enhances ceramide concentration by facilitating its self-assembly at the interface. This work was supported by the Korea National Research Foundation NRF(RS-2023-00302586, RS-2023-00212739), Republic of Korea.